Chronic Kidney Disease (CKD) Genetic Risk Report

1 in 3 adults in the United States are at risk of CKD, almost none of them is aware of it, resulting in 40% of people with severely reduced kidney function having undiagnosed CKD.

While African -Americans make up about 13 percent of the population, they account for 35 percent of the people with kidney failure in the United States.

Take a DNA Test to understand your predisposition risk to  Chronic Kidney Disease.

 


Silverberry solution to CKD is focused on early risk assessment and targeted intervention. It is a combination of genetic testing assessment, followed by diet, and lifestyle recommendations tailored to you.

 


Genetic Factors of Health Disparity


What is CKD Risk?

Chronic kidney disease (CKD) is a condition characterized by a gradual loss of kidney function over time. CDK includes conditions that damage your kidneys and decrease their ability to keep you healthy by doing the jobs listed. If kidney disease gets worse, wastes can build to high levels in your blood and make you feel sick. You may develop complications like high blood pressure, anemia (low blood count), weak bones, poor nutritional health and nerve damage. Chronic kidney disease may be caused by diabetes, high blood pressure and other disorders. Early detection and treatment can often keep chronic kidney disease from getting worse. When kidney disease progresses, it may eventually lead to kidney failure, which requires dialysis or a kidney transplant to maintain life.

37 million American adults have CKD and millions of others are at increased risk. Individuals with recent African ancestry carry an excessive burden of CKD and compared to individuals of other ancestries. Individuals with recent African ancestry are 4 times as likely as white people to develop kidney failure. A variant of the APOL1 gene increases the chance of kidney failure in people with up to 70%. Importantly, people of African ancestry have a higher frequency of the risk alleles compared with the rest of the community.

 

Order your report to receive your personal risk report

It's all about you

Easy to Understand

Your results is written for you. View online or download to share your reports with your healthcare provider, personal trainer, family or friends.

Personalized

View your personalized assessment including a summary, description of each trait plus genetic variations included in your assessment.

Actionable

In addition to list of actions to take, through Genei.us membership, comprehensive recommendations are provided linked to each trait.

Items such as recipe, exercise, supplement, health gear and beauty products.

 


Order your kit or CKD Risk Report

Have a DNA File?

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Existing Silverberry Customer?

Notes and disclaimer:

  • Silverberry CKD DNA Test is NOT a diagnostic, monitoring, or treatment test. It solely measures predisposition risk to the disease based on genetic factors.
  • If you have an existing DNA File and it includes information about the genetic variations needed to assess your risk, you will receive your reports online immediately.
  • If your file does not include the genetic information needed for the risk assessment, you need to take a DNA Test with Silverberry. This is a pre-order and your results will be available approximately 90 days from the time that your saliva sample is received at the lab.
  • If you have taken a DNA test with Silverberry and you see Unknown Results, you need to order a re-processing DNA Test. The approximate timeline to generate the new file and produce your report is 90 days from the time of order.
  • Recipe recommendation for a kidney-friendly diet is available under genei.us membership by using Silverberry mobile app.

Why are minority populations at greater risk for kidney disease?

Some minority populations are more likely to have diabetes as compared to White Americans. In fact, 13% of Black or African-Americans adults and 13.2% of Hispanic or Latino adults have been diagnosed with diabetes. American Indians and Alaska Natives are twice as likely to have diabetes as White-Americans. Having diabetes can lead to kidney disease and kidney failure.
The rates of kidney failure caused by diabetes have doubled in Asian Americans ages 30-39 between 2000-2010. Diabetes also causes kidney failure more often in Hispanics or Latinos than in White Americans.
High blood pressure is also a serious problem for minorities. High blood pressure strikes more than 1 out of 3 Blacks or African Americans, one of the highest rates in the world. Nearly 1 in 4 Hispanics or Latinos has high blood pressure and most do not know that high blood pressure can cause kidney disease. (Source: National Kidney Foundation)
Another factor is African Sleeping Sickness. Due to genetic mutation to the disease, predisposition to CKD has increased among individuals with African Ancestry. Click here to learn more.